Support Weight Loss Medications- Semaglutide

GLP-1 receptor agonist for diabetes treatment and weight management

Proven Weight Loss Solution

12-15%

Average Weight Loss

Clinically Proven Results

Sustainable Weight Loss

Achieve lasting results with 12-15% average weight loss maintained over time

Cardiovascular Protection

Reduces risk of major cardiovascular events by 20%

Multiple Forms Available

Choose between weekly injection or daily oral tablet for your lifestyle

Why Semaglutide is Your Weight Loss Solution

Semaglutide is a groundbreaking glucagon-like peptide-1 (GLP-1) receptor agonist that has revolutionized weight management and diabetes treatment. Originally developed for type 2 diabetes, its remarkable weight loss effects have made it the go-to choice for sustainable, medically-supervised weight management.

Patient Success Story:

"After struggling with weight for years, Semaglutide finally gave me the control I needed. I've lost 38 pounds and kept it off for over a year." - Michael R.

Mechanism of Action

  • Insulin Secretion: Stimulates glucose-dependent insulin release from pancreatic beta cells

  • Glucagon Suppression: Reduces glucagon secretion from pancreatic alpha cells when glucose levels are elevated

  • Gastric Emptying: Slows gastric emptying, promoting satiety and reducing post-meal glucose spikes

  • Central Appetite Control: Acts on hypothalamic receptors to reduce appetite and food intake

  • Beta Cell Preservation: May help preserve pancreatic beta cell function

Transformation Results

Diabetes Management:

  • Significant reduction in HbA1c levels

  • Improved glycemic control

  • Low risk of hypoglycemia

  • Cardiovascular benefits

Weight Management Success:

  • Average weight loss of 15-22% in clinical trials

  • Sustained weight reduction

  • Improved body composition

  • Reduction in waist circumference

Clinical Trial Highlights:

n the SURMOUNT trials, patients achieved an average of 20.9% weight loss at the highest dose - results that exceeded all expectations and set new standards in weight management therapy.

Dosing and Administration

Route: Subcutaneous injection once weekly
Starting Dose: 2.5 mg once weekly for 4 weeks
Maintenance Doses:

  • 5 mg once weekly (minimum effective dose)

  • 7.5 mg once weekly

  • 10 mg once weekly

  • 12.5 mg once weekly

  • 15 mg once weekly (maximum dose)

Injection Sites: Thigh, abdomen, or upper arm. Rotate injection sites weekly.

Side Effects

Common (≥5%):

  • Nausea (12-18%)

  • Diarrhea (12-16%)

  • Vomiting (6-12%)

  • Constipation (6-7%)

  • Abdominal pain (6-9%)

  • Injection site reactions

Serious (Rare):

  • Pancreatitis

  • Gallbladder disease

  • Kidney problems

  • Severe hypoglycemia (when combined with insulin/sulfonylureas)

  • Thyroid C-cell tumors (theoretical risk)

Contraindications & Precautions

Contraindications:

  • Personal or family history of medullary thyroid carcinoma

  • Multiple Endocrine Neoplasia syndrome type 2

  • Known hypersensitivity to tirzepatide

Use with Caution:

  • History of pancreatitis

  • Severe renal impairment

  • Diabetic retinopathy

  • Pregnancy and breastfeeding

Disclaimer: I.R.I.S.E. Inc. provides transformation coaching, meal plans, and products—including the 12-Week Transformation Program and the 12-Week Transformation Enhanced Program—for informational and educational purposes only. This content is not intended to replace medical advice, diagnosis, or treatment. Always consult with your physician or a qualified healthcare provider regarding any medical questions or before beginning a new wellness program. Disclaimer: No Medical Advice

Privacy & HIPAA: We maintain a secure platform, and all personal health information is protected in compliance with HIPAA regulations. Clients are required to sign both a HIPAA Consent Form and a Non-Disclosure Agreement (NDA). All materials, plans, and content provided by I.R.I.S.E. are for personal use only and must not be copied, duplicated, or shared outside of the client receiving services.

Results Disclaimer: Individual weight-loss results vary based on effort, commitment, and adherence to the program. I.R.I.S.E. Inc. makes no guarantees of specific outcomes.

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