The Anti-Aging Breakthrough
The Fountain of Youth at the Cellular Level
NAD+ is being hailed as the most important anti-aging discovery of our time. This critical coenzyme, found in every cell of your body, is essential for energy production, DNA repair, and activating the "longevity proteins" that slow aging. Unfortunately, NAD+ levels decline by 50% between ages 40-60, leading to fatigue, cognitive decline, and accelerated aging.
Patient Success Story:
"Within two weeks of starting NAD+ therapy, I had energy I hadn't felt in 20 years. My mind is sharp, my workouts are intense, and people keep asking what I'm doing differently." - Jennifer K., Age 52
Energy Metabolism: Essential cofactor in glycolysis, citric acid cycle, and oxidative phosphorylation
DNA Repair: Required for poly(ADP-ribose) polymerase (PARP) enzymes that repair DNA damage
Sirtuin Activation: Serves as substrate for sirtuin enzymes (longevity proteins) that regulate aging processes
Cellular Signaling: Involved in calcium signaling and cyclic ADP-ribose production
Circadian Rhythm: Plays a role in maintaining cellular circadian clocks
Mitochondrial Function: Critical for mitochondrial biogenesis and function
NAD+ levels decrease by ~50% between ages 40-60
Reduced NAD+ biosynthesis enzymes
Increased NAD+ consumption by DNA repair enzymes
Decreased efficiency of mitochondrial respiration
Average weight loss of 15-22% in clinical trials
Sustained weight reduction
Improved body composition
Reduction in waist circumference
The Aging Crisis:
By age 50, you have half the NAD+ you had at 20. This dramatic decline is directly linked to why you feel older, tire easier, and struggle with the energy you once had.
Dramatically improved energy levels
Enhanced fat burning and metabolism
Better glucose control
Increased exercise capacity
Natural weight management support
Activated longevity pathways
Enhanced DNA repair
Improved skin health and appearance
Slower cellular aging
Increased lifespan potential
Direct bioavailability
Rapid cellular uptake
Typical dose: 250-500mg
Professional administration required
Good bioavailability
Self-administration possible
Lower doses than oral
Gradual absorption
Nicotinamide Riboside (NR)
Nicotinamide Mononucleotide (NMN)
Variable bioavailability
Convenient daily dosing
Nicotinamide riboside supplementation increased NAD+ levels by 60% in healthy adults
Improved insulin sensitivity in prediabetic individuals
Enhanced mitochondrial function in older adults
Potential cardiovascular benefits in small trials
Extended lifespan in various animal models
Improved cognitive function and neuroprotection
Enhanced muscle function and exercise capacity
Protection against age-related metabolic decline
NAD+ is naturally occurring in the body
Minimal side effects in clinical trials
No serious adverse events reported
Safe profile in healthy adults
Mild nausea (with high oral doses)
Flushing (with IV administration)
Fatigue (rare, usually temporary)
Headache (uncommon)
Individual Response: Effects may vary based on baseline NAD+ levels and individual metabolism
Timing: Some evidence suggests morning administration may be optimal for circadian rhythm support
Lifestyle Factors: Exercise, caloric restriction, and adequate sleep naturally support NAD+ levels
Quality: Choose pharmaceutical-grade NAD+ from reputable compounding pharmacies
Monitoring: Regular assessment of energy levels, sleep quality, and overall well-being
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Results Disclaimer: Individual weight-loss results vary based on effort, commitment, and adherence to the program. I.R.I.S.E. Inc. makes no guarantees of specific outcomes.
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