Clinically Proven Results
Why Choose Tirzepatide?
Tirzepatide represents the latest breakthrough in weight management and diabetes treatment. As a novel dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist, it offers unprecedented results for patients seeking effective, long-term solutions.
Real Patient Success:
"I lost 45 pounds in 6 months with Tirzepatide. My energy is back, my diabetes is under control, and I feel like myself again." - Sarah M.
GLP-1 Receptor Activation: Stimulates insulin secretion in a glucose-dependent manner, suppresses glucagon release, and slows gastric emptying
GIP Receptor Activation: Enhances insulin sensitivity and may have direct effects on fat metabolism
Appetite Regulation: Acts on brain receptors to reduce appetite and food intake
Gastric Motility: Slows gastric emptying, leading to increased satiety
Significant reduction in HbA1c levels
Improved glycemic control
Low risk of hypoglycemia
Cardiovascular benefits
Average weight loss of 15-22% in clinical trials
Sustained weight reduction
Improved body composition
Reduction in waist circumference
Clinical Trial Highlights:
In the SURMOUNT trials, patients achieved an average of 20.9% weight loss at the highest dose - results that exceeded all expectations and set new standards in weight management therapy.
5 mg once weekly (minimum effective dose)
7.5 mg once weekly
10 mg once weekly
12.5 mg once weekly
15 mg once weekly (maximum dose)
Nausea (12-18%)
Diarrhea (12-16%)
Vomiting (6-12%)
Constipation (6-7%)
Abdominal pain (6-9%)
Injection site reactions
Pancreatitis
Gallbladder disease
Kidney problems
Severe hypoglycemia (when combined with insulin/sulfonylureas)
Thyroid C-cell tumors (theoretical risk)
Personal or family history of medullary thyroid carcinoma
Multiple Endocrine Neoplasia syndrome type 2
Known hypersensitivity to tirzepatide
History of pancreatitis
Severe renal impairment
Diabetic retinopathy
Pregnancy and breastfeeding
Disclaimer: I.R.I.S.E. Inc. provides transformation coaching, meal plans, and products—including the 12-Week Transformation Program and the 12-Week Transformation Enhanced Program—for informational and educational purposes only. This content is not intended to replace medical advice, diagnosis, or treatment. Always consult with your physician or a qualified healthcare provider regarding any medical questions or before beginning a new wellness program. Disclaimer: No Medical Advice
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Results Disclaimer: Individual weight-loss results vary based on effort, commitment, and adherence to the program. I.R.I.S.E. Inc. makes no guarantees of specific outcomes.
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